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six years after it was known that there was no difference between synthroid and generic levothyroxine products, and more than two years after the ucsf research should have been published, the journal of the american medical association published the research just as it would have appeared in january 1995, had it not been for boots s interference.

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because it is known that levothyroxine is susceptible to the loss of active ingredient over time, fda contended that knoll used the method of overage adding more active ingredient in the production phase, anticipating its loss by the point of oral administration that ranged over the course of synthroid s production history.

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