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it will explore this topic on several fronts namely a evidence of efficacy of primaquine for its current indications; b potential hazards of its widespread use c critical analysis of reported resistance against primaquine containing regimens d evidence for combining primaquine with artemisinins in areas of chloroquine resistance and e the potential for replacement of primaquine with newer drugs.

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chloroquine is slowly being replaced by sulfonamide-pyrimethamine combinations in many parts of africa.

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